- 《英文msh詞典》Second Generation Antihistamines
- [入口詞] Second Generation Antihistamines
- [主題詞] Histamine H1 Antagonists,Non-Sedating
- [英文釋義] A class of non-sedating drugs that bind to but do not activate histamine receptors,thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures,adverse effects,distribution,and metabolism. Compared to the early (first generation) antihistamines,these non-sedating antihistamines have greater receptor specificity,lower penetration of BLOOD-BRAIN BARRIER,and are less likely to cause drowsiness or psychomotor impairment.
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